{
  "query": "ARWR",
  "resolved": {
    "ticker": "ARWR",
    "cik": "0000879407",
    "title": "ARROWHEAD PHARMACEUTICALS, INC."
  },
  "signals": [
    {
      "type": "trial_to_filing",
      "headline": "ARROWHEAD PHARMACEUTICALS, INC. (ARWR) — PHASE2 protocol updated 1 days ago",
      "entity": "Arrowhead Pharmaceuticals",
      "ticker": "ARWR",
      "cik": "0000879407",
      "tickerConfidence": 0.95,
      "upstream": {
        "event": "Clinical trial status (PHASE2)",
        "detail": "Study of ARO-MAPT-SC in Healthy Participants and Participants With Early Alzheimer's Disease",
        "nctId": "NCT07221344",
        "date": "2027-06"
      },
      "observed": {
        "event": "protocol updated 1 days ago",
        "nctId": "NCT07221344"
      },
      "predicted": {
        "event": "SEC 8-K / press release on Phase 3 initiation",
        "leadTime": "18-36 mo",
        "baseRate": 0.29,
        "note": "Reg FD requires prompt disclosure of material clinical results."
      },
      "leadTime": "Phase-transition base rate 28% (Wong/Siah/Lo 2019)",
      "confidence": 0.35,
      "links": {
        "trial": "https://clinicaltrials.gov/study/NCT07221344",
        "filings": "https://www.sec.gov/cgi-bin/browse-edgar?action=getcompany&CIK=0000879407&type=8-K"
      }
    }
  ],
  "recentFilings": {
    "name": "ARROWHEAD PHARMACEUTICALS, INC.",
    "sicDescription": "Pharmaceutical Preparations",
    "filings": [
      {
        "form": "8-K",
        "date": "2026-08-04",
        "accession": "0000879407-26-000058",
        "items": "2.02,9.01"
      },
      {
        "form": "8-K",
        "date": "2026-06-16",
        "accession": "0000879407-26-000050",
        "items": "5.02,9.01"
      },
      {
        "form": "8-K",
        "date": "2026-05-07",
        "accession": "0000879407-26-000045",
        "items": "2.02,9.01"
      },
      {
        "form": "8-K",
        "date": "2026-03-20",
        "accession": "0000879407-26-000037",
        "items": "5.07,9.01"
      },
      {
        "form": "8-K",
        "date": "2026-02-05",
        "accession": "0000879407-26-000033",
        "items": "2.02,9.01"
      }
    ]
  },
  "disclaimer": "Research/informational. NOT investment advice.",
  "generatedAt": "2026-09-19T09:01:05.471Z"
}